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Cheap bus tickets from Des Moines, IA to Panama City, FL

from 188,98 €

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What to expect of your trip

Fast, easy, and affordable options from Des Moines, IA to Panama City, FL

Avg. trip duration

35 hr 3 mins

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Avg. distance

3110 km

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Cheapest trip

From 188,98 €

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2

Avg. trips a day

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On this page

Bus stations and stops in Des Moines, IA

Please note: your ticket will contain the most up-to-date address information.
Best service on board
Available options you can find for a more comfortable trip:
wifi
Free WiFi
Stay connected throughout your journey
socket
Power Outlets
Keep your devices charged on the go
seat
Comfortable seats
Relax with extra legroom and reclining seats
luggage
Luggage storage
Space to safely stow your belongings
toilet
Toilets
Conveniently available on every FlixBus
First time travelling with us?
More on our service
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Onboard services are subject to availability

Where to next?
Discover our travel map with over 8000 destinations worldwide.
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Vehicle passing through a city

Digital ticket & Live tracking

Discover the FlixBus app

Book trips
Your tickets
Track your trip
Always in-the-know
Get it on Google Play Download on the App Store
FlixBus app on phone

Scan to download the App

Trusted by 500+ million passengers

Frequently asked questions

With FlixBus, you can conveniently reach 11 destinations from Panama City, including Orlando, Tallahassee, Fort Lauderdale.
Yes, weekend trip options are available from Des Moines to Panama City. Check out the route's schedule and chose the best option to suit your plans!
Yes, night trip options are available from Des Moines to Panama City. Check out the route's schedule and choose the best option to suit your plans!
Passengers traveling from Des Moines to Panama City can bring one checked luggage and one piece of hand luggage for free. If you want to carry additional or special luggage, you can check all the options available on this page.
Yes, all FlixBus buses from Des Moines to Panama City are equipped for passengers with reduced mobility. We strive to make our buses as comfortable and accessible as possible for people with disabilities and limited mobility. Service animals are allowed on board all FlixBus buses traveling from Des Moines to Panama City. The transportation of wheelchairs, foldable wheelchairs, walking aid and other assistive mobility devices is free of charge.
Traveling by bus from Des Moines to Panama City is one of the most environmentally-friendly options available as it reduces traffic associated emissions, and passengers can offset their carbon emissions when they travel with FlixBus by clicking the CO₂ compensation box when booking their ticket.
FlixBus buses traveling from Des Moines to Panama City offer extra legroom, private outlets, and restrooms. Most buses also provide free Wi-Fi.
The earliest FlixBus ride from Des Moines to Panama City departs at 00:01.
The latest FlixBus ride from Des Moines to Panama City departs at 23:45.
There is one bus station in Des Moines; Des Moines. You can find its location on the map on his page.
There is one bus station in Panama City; Panama City Beach Bus Station. You can find its location on the map on his page.
No, you don't need to print your ticket if you purchased it online or via the app. Simply show the driver the QR code that you received via email or that is stored in the app and you're ready to travel from Des Moines to Panama City. It's that easy!
The price of a children's bus ticket from Des Moines to Panama City depends on the age of the child and the time of booking. Children under the age of 15 receive a discount on the regular adult fare. At the time of booking, we calculate the cheapest price for you from all available rates and discounts. If the discounted price is lower than the child fare, the selected passengers pay the same price. Please, make sure you check our child travel and seat policy. Strollers and foldable pushchairs (width + length + height = max 240 cm) can be transported in the luggage compartment of the bus free of charge.
We offer several payment methods for purchasing your ticket from Des Moines to Panama City securely. You can choose among card payment, PayPal, Google Pay and many more. Once in the payment section, you will be able to see all the available options and pick your preferred one. If you are having difficulties with payment, check out our help page about payments. If you buy your bus ticket onboard or at a sales point you are also given the option to pay cash.
You can get from Des Moines to Panama City for as little as 187,98 €. Take advantage of our best deals on FlixBus tickets by traveling off-peak and during the week. You can buy your ticket from Des Moines to Panama City most easily on this website or in the app.
When traveling from Des Moines to Panama City, you can track your bus location on our Real-Time Bus Tracker. Just select the relevant bus stop and check the time of arrival. Find out where your bus is and check if there are delays on the route.

Looking for bus tickets from Des Moines to Panama City?

Look no further, we’ve got all the details you need to plan your bus trip! The journey Des Moines to Panama City takes as little as 34 hours 20 minutes and can cost as little as 187,98 €. The first bus leaves at 00:01 and the last bus leaves at 23:45. FlixBus runs 3 rides each day between Des Moines and Panama City and when travelling with FlixBus, you can expect free Wifi, power sockets and a guaranteed seat for your journey.