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Cheap bus tickets from Des Moines, IA to San Francisco, CA

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Bus stations and stops in Des Moines, IA

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Frequently asked questions

Yes, night trip options are available from Des Moines to San Francisco. Check out the route's schedule and choose the best option to suit your plans!
With FlixBus, you can conveniently reach 36 destinations from San Francisco, including Los Angeles, Sacramento, Reno/Sparks.
We offer several payment methods for purchasing your ticket from Des Moines to San Francisco securely. You can choose among card payment, PayPal, Google Pay and many more. Once in the payment section, you will be able to see all the available options and pick your preferred one. If you are having difficulties with payment, check out our help page about payments. If you buy your bus ticket onboard or at a sales point you are also given the option to pay cash.
When traveling from Des Moines to San Francisco, you can track your bus location on our Real-Time Bus Tracker. Just select the relevant bus stop and check the time of arrival. Find out where your bus is and check if there are delays on the route.
Passengers traveling from Des Moines to San Francisco can bring one checked luggage and one piece of hand luggage for free. If you want to carry additional or special luggage, you can check all the options available on this page.
The price of a children's bus ticket from Des Moines to San Francisco depends on the age of the child and the time of booking. Children under the age of 15 receive a discount on the regular adult fare. At the time of booking, we calculate the cheapest price for you from all available rates and discounts. If the discounted price is lower than the child fare, the selected passengers pay the same price. Please, make sure you check our child travel and seat policy. Strollers and foldable pushchairs (width + length + height = max 240 cm) can be transported in the luggage compartment of the bus free of charge.
Yes, all FlixBus buses from Des Moines to San Francisco are equipped for passengers with reduced mobility. We strive to make our buses as comfortable and accessible as possible for people with disabilities and limited mobility. Service animals are allowed on board all FlixBus buses traveling from Des Moines to San Francisco. The transportation of wheelchairs, foldable wheelchairs, walking aid and other assistive mobility devices is free of charge.
Traveling by bus from Des Moines to San Francisco is one of the most environmentally-friendly options available as it reduces traffic associated emissions, and passengers can offset their carbon emissions when they travel with FlixBus by clicking the CO₂ compensation box when booking their ticket.
FlixBus buses traveling from Des Moines to San Francisco offer extra legroom, private outlets, and restrooms. Most buses also provide free Wi-Fi.
The earliest FlixBus ride from Des Moines to San Francisco departs at 05:30.
There are 2 bus stations in Des Moines; Des Moines, Des Moines (Subway). You can find the location of the stations on the map on this page.
There are 4 bus stations in San Francisco; Daly City BART Station, San Francisco (5th/Townsend), San Francisco Bus Station, San Francisco Fisherman’s Wharf (Hyde/Beach). You can find the location of the stations on the map on this page.
No, you don't need to print your ticket if you purchased it online or via the app. Simply show the driver the QR code that you received via email or that is stored in the app and you're ready to travel from Des Moines to San Francisco. It's that easy!
The latest FlixBus ride from Des Moines to San Francisco departs at 23:45.

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