Skip to main content

Cheap bus tickets from Knoxville, TN to Des Moines, IA

from 137,99 €

Health and Safety

Keep yourself and others safe while traveling with us.
Learn more

Comfort on board

Our buses are equipped with large and comfortable seats, a toilet, Wi-Fi and power outlets.
Our onboard service

Largest bus network in Europe

Choose from over 3,000 travel destinations in 40+ countries and discover Europe with FlixBus.
Our route network

Travel environmentally-friendly

Our efficient coaches are proven to have an excellent carbon footprint per driven passenger-kilometer.
Bus travel and environment

On this page

Bus stations and stops in Knoxville, TN

Please note: your ticket will contain the most up-to-date address information.

Discover all destinations

Frequently asked questions

With FlixBus, you can conveniently reach 51 destinations from Des Moines, including Chicago, Minneapolis, Iowa City.
Yes, night trip options are available from Knoxville to Des Moines. Check out the route's schedule and choose the best option to suit your plans!
You can get from Knoxville to Des Moines for as little as 137,99 €. Take advantage of our best deals on FlixBus tickets by traveling off-peak and during the week. You can buy your ticket from Knoxville to Des Moines most easily on this website or in the app.
When traveling from Knoxville to Des Moines, you can track your bus location on our Real-Time Bus Tracker. Just select the relevant bus stop and check the time of arrival. Find out where your bus is and check if there are delays on the route.
We offer several payment methods for purchasing your ticket from Knoxville to Des Moines securely. You can choose among card payment, PayPal, Google Pay and many more. Once in the payment section, you will be able to see all the available options and pick your preferred one. If you are having difficulties with payment, check out our help page about payments. If you buy your bus ticket onboard or at a sales point you are also given the option to pay cash.
Passengers traveling from Knoxville to Des Moines can bring one checked luggage and one piece of hand luggage for free. If you want to carry additional or special luggage, you can check all the options available on this page.
The price of a children's bus ticket from Knoxville to Des Moines depends on the age of the child and the time of booking. Children under the age of 15 receive a discount on the regular adult fare. At the time of booking, we calculate the cheapest price for you from all available rates and discounts. If the discounted price is lower than the child fare, the selected passengers pay the same price. Please, make sure you check our child travel and seat policy. Strollers and foldable pushchairs (width + length + height = max 240 cm) can be transported in the luggage compartment of the bus free of charge.
Yes, all FlixBus buses from Knoxville to Des Moines are equipped for passengers with reduced mobility. We strive to make our buses as comfortable and accessible as possible for people with disabilities and limited mobility. Service animals are allowed on board all FlixBus buses traveling from Knoxville to Des Moines. The transportation of wheelchairs, foldable wheelchairs, walking aid and other assistive mobility devices is free of charge.
Traveling by bus from Knoxville to Des Moines is one of the most environmentally-friendly options available as it reduces traffic associated emissions, and passengers can offset their carbon emissions when they travel with FlixBus by clicking the CO₂ compensation box when booking their ticket.
FlixBus buses traveling from Knoxville to Des Moines offer extra legroom, private outlets, and restrooms. Most buses also provide free Wi-Fi.
The earliest FlixBus ride from Knoxville to Des Moines departs at 18:45.
The latest FlixBus ride from Knoxville to Des Moines departs at 22:30.
There is one bus station in Knoxville; Knoxville Area Transit Bus Stop. You can find its location on the map on his page.
No, you don't need to print your ticket if you purchased it online or via the app. Simply show the driver the QR code that you received via email or that is stored in the app and you're ready to travel from Knoxville to Des Moines. It's that easy!
There are 2 bus stations in Des Moines; Des Moines, Des Moines (Subway). You can find the location of the stations on the map on this page.

Looking for bus tickets from Knoxville to Des Moines?

Look no further, we’ve got all the details you need to plan your bus trip! The journey Knoxville to Des Moines takes as little as 22 hours 50 minutes and can cost as little as 137,99 €. The first bus leaves at 18:45 and the last bus leaves at 22:30. FlixBus runs 3 rides each day between Knoxville and Des Moines and when travelling with FlixBus, you can expect free Wifi, power sockets and a guaranteed seat for your journey.

Onboard services are subject to availability