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Cheap bus tickets from Knoxville, TN to Key West, FL

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Fast, easy, and affordable options from Knoxville, TN to Key West, FL

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Bus stations and stops in Knoxville, TN

Please note: your ticket will contain the most up-to-date address information.
Best service on board
Available options you can find for a more comfortable trip:
wifi
Free WiFi
Stay connected throughout your journey
socket
Power Outlets
Keep your devices charged on the go
seat
Comfortable seats
Relax with extra legroom and reclining seats
luggage
Luggage storage
Space to safely stow your belongings
toilet
Toilets
Conveniently available on every FlixBus
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Onboard services are subject to availability

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Discover our travel map with over 8000 destinations worldwide.
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Vehicle passing through a city

Digital ticket & Live tracking

Discover the FlixBus app

Book trips
Your tickets
Track your trip
Always in-the-know
Get it on Google Play Download on the App Store
FlixBus app on phone

Scan to download the App

Trusted by 500+ million passengers

Frequently asked questions

The bus route from Knoxville to Key West covers 2262 km. FlixBus can bring you from Knoxville to Key West in 37 hours 50 minutes.
When traveling from Knoxville to Key West, you can track your bus location on our Real-Time Bus Tracker. Just select the relevant bus stop and check the time of arrival. Find out where your bus is and check if there are delays on the route.
We offer several secure payment methods for purchasing your ticket from Knoxville to Key West. You can pay using debit or credit card, PayPal, Google Pay, and other options. All available payment methods will be displayed during checkout so you can choose the one that suits you best. If you experience payment issues, check that your payment details are correct, your card is enabled for online or international transactions, and that you have sufficient funds. If you buy your bus ticket onboard or at a sales point, you may also have the option to pay in cash.
Passengers traveling from Knoxville to Key West with FlixBus can bring one piece of checked luggage and one piece of hand luggage free of charge. Your hand luggage should fit in the overhead compartment or under your seat, while larger bags are stored in the bus’s luggage compartment. If you want to bring additional or special luggage, you can find all available options on our luggage allowance.
Traveling by bus from Knoxville to Key West is one of the most environmentally-friendly options available as it reduces traffic associated emissions, and passengers can offset their carbon emissions when they travel with FlixBus by clicking the CO₂ compensation box when booking their ticket.
FlixBus buses traveling from Knoxville to Key West offer extra legroom, private outlets, and restrooms. Most buses also provide free Wi-Fi.
The first FlixBus from Knoxville to Key West departs at 19:40, while the last departure is at 22:50. Departure times may vary depending on the day and route, so it’s always advisable to check the schedule before you book your bus ticket.
There is one bus station in Key West. You can find its location on the map on his page.
There is one bus stop in Knoxville. You can find its location on the map on his page.
No, you don't need to print your ticket if you purchased it online or via the app. Simply show the driver the QR code that you received via email or that is stored in the app and you're ready to travel from Knoxville to Key West. It's that easy!
With FlixBus, you can conveniently reach 5 destinations from Key West, including Miami, Fort Lauderdale, Marathon.
Yes, night buses from Knoxville to Key West are available, offering a convenient way to travel overnight and save time during the day. Overnight bus trips can also help you reduce accommodation costs while making the most of your journey.

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