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Cheap bus tickets from Madrid to Palermo

from 292,99 €

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Bus stations and stops in Madrid

Please note: your ticket will contain the most up-to-date address information.

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Frequently asked questions

Yes, night trip options are available from Madrid to Palermo. Check out the route's schedule and choose the best option to suit your plans!
With FlixBus, you can conveniently reach 41 destinations from Palermo, including Catania, Rome, Milan.
We offer several payment methods for purchasing your ticket from Madrid to Palermo securely. You can choose among card payment, PayPal, Google Pay and many more. Once in the payment section, you will be able to see all the available options and pick your preferred one. If you are having difficulties with payment, check out our help page about payments. If you buy your bus ticket onboard or at a sales point you are also given the option to pay cash.
You can get from Madrid to Palermo for as little as 292,99 €. Take advantage of our best deals on FlixBus tickets by traveling off-peak and during the week. You can buy your ticket from Madrid to Palermo most easily on this website or in the app.
When traveling from Madrid to Palermo, you can track your bus location on our Real-Time Bus Tracker. Just select the relevant bus stop and check the time of arrival. Find out where your bus is and check if there are delays on the route.
Passengers traveling from Madrid to Palermo can bring one checked luggage and one piece of hand luggage for free. If you want to carry additional or special luggage, you can check all the options available on this page.
The price of a children's bus ticket from Madrid to Palermo depends on the age of the child and the time of booking. Children under the age of 15 receive a discount on the regular adult fare. At the time of booking, we calculate the cheapest price for you from all available rates and discounts. If the discounted price is lower than the child fare, the selected passengers pay the same price. Please, make sure you check our child travel and seat policy. Strollers and foldable pushchairs (width + length + height = max 240 cm) can be transported in the luggage compartment of the bus free of charge.
Yes, all FlixBus buses from Madrid to Palermo are equipped for passengers with reduced mobility. We strive to make our buses as comfortable and accessible as possible for people with disabilities and limited mobility. Service animals are allowed on board all FlixBus buses traveling from Madrid to Palermo. The transportation of wheelchairs, foldable wheelchairs, walking aid and other assistive mobility devices is free of charge.
Traveling by bus from Madrid to Palermo is one of the most environmentally-friendly options available as it reduces traffic associated emissions, and passengers can offset their carbon emissions when they travel with FlixBus by clicking the CO₂ compensation box when booking their ticket.
FlixBus buses traveling from Madrid to Palermo offer extra legroom, private outlets, and restrooms. Most buses also provide free Wi-Fi.
The earliest FlixBus ride from Madrid to Palermo departs at 19:15.
There are 2 bus stations in Madrid; MADRID AUTOGARA, Madrid (South Bus Station). You can find the location of the stations on the map on this page.
There are 3 bus stations in Palermo; Palermo (Piazza Cairoli), Palermo (Via Fazello), Palermo Autostazione. You can find the location of the stations on the map on this page.
No, you don't need to print your ticket if you purchased it online or via the app. Simply show the driver the QR code that you received via email or that is stored in the app and you're ready to travel from Madrid to Palermo. It's that easy!
The latest FlixBus ride from Madrid to Palermo departs at 20:50.

Looking for bus tickets from Madrid to Palermo?

Look no further, we’ve got all the details you need to plan your bus trip! The journey Madrid to Palermo takes as little as 48 hours 10 minutes and can cost as little as 292,99 €. The first bus leaves at 19:15 and the last bus leaves at 20:50. FlixBus runs 2 rides each day between Madrid and Palermo and when travelling with FlixBus, you can expect free Wifi, power sockets and a guaranteed seat for your journey.

Onboard services are subject to availability