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Cheap bus tickets from Panama City, FL to Des Moines, IA

from 188,98 €

What to expect of your trip

Fast, easy, and affordable options from Panama City, FL to Des Moines, IA

Avg. trip duration

36 hr 40 mins

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Avg. distance

2607 km

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Cheapest trip

From 188,98 €

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1

Avg. trips a day

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On this page

Bus stations and stops in Panama City, FL

Please note: your ticket will contain the most up-to-date address information.

Onboard services are subject to availability

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Frequently asked questions

Passengers traveling from Panama City to Des Moines can bring one checked luggage and one piece of hand luggage for free. If you want to carry additional or special luggage, you can check all the options available on this page.
The price of a children's bus ticket from Panama City to Des Moines depends on the age of the child and the time of booking. Children under the age of 15 receive a discount on the regular adult fare. At the time of booking, we calculate the cheapest price for you from all available rates and discounts. If the discounted price is lower than the child fare, the selected passengers pay the same price. Please, make sure you check our child travel and seat policy. Strollers and foldable pushchairs (width + length + height = max 240 cm) can be transported in the luggage compartment of the bus free of charge.
Yes, all FlixBus buses from Panama City to Des Moines are equipped for passengers with reduced mobility. We strive to make our buses as comfortable and accessible as possible for people with disabilities and limited mobility. Service animals are allowed on board all FlixBus buses traveling from Panama City to Des Moines. The transportation of wheelchairs, foldable wheelchairs, walking aid and other assistive mobility devices is free of charge.
Traveling by bus from Panama City to Des Moines is one of the most environmentally-friendly options available as it reduces traffic associated emissions, and passengers can offset their carbon emissions when they travel with FlixBus by clicking the CO₂ compensation box when booking their ticket.
FlixBus buses traveling from Panama City to Des Moines offer extra legroom, private outlets, and restrooms. Most buses also provide free Wi-Fi.
The earliest FlixBus ride from Panama City to Des Moines departs at 07:30.
The latest FlixBus ride from Panama City to Des Moines departs at 21:40.
There is one bus station in Panama City; Panama City Beach Bus Station. You can find its location on the map on his page.
There is one bus station in Des Moines; Des Moines. You can find its location on the map on his page.
No, you don't need to print your ticket if you purchased it online or via the app. Simply show the driver the QR code that you received via email or that is stored in the app and you're ready to travel from Panama City to Des Moines. It's that easy!
With FlixBus, you can conveniently reach 61 destinations from Des Moines, including Chicago, Minneapolis, Iowa City.
Yes, night trip options are available from Panama City to Des Moines. Check out the route's schedule and choose the best option to suit your plans!
We offer several payment methods for purchasing your ticket from Panama City to Des Moines securely. You can choose among card payment, PayPal, Google Pay and many more. Once in the payment section, you will be able to see all the available options and pick your preferred one. If you are having difficulties with payment, check out our help page about payments. If you buy your bus ticket onboard or at a sales point you are also given the option to pay cash.
You can get from Panama City to Des Moines for as little as 188,98 €. Take advantage of our best deals on FlixBus tickets by traveling off-peak and during the week. You can buy your ticket from Panama City to Des Moines most easily on this website or in the app.
When traveling from Panama City to Des Moines, you can track your bus location on our Real-Time Bus Tracker. Just select the relevant bus stop and check the time of arrival. Find out where your bus is and check if there are delays on the route.

Looking for bus tickets from Panama City to Des Moines?

Look no further, we’ve got all the details you need to plan your bus trip! The journey Panama City to Des Moines takes as little as 35 hours and can cost as little as 188,98 €. The first bus leaves at 07:30 and the last bus leaves at 21:40. FlixBus runs daily rides between Panama City and Des Moines and when travelling with FlixBus, you can expect free Wifi, power sockets and a guaranteed seat for your journey.
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