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Cheap bus tickets from Panama City, FL to Sioux Falls, SD

from 186,98 €

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What to expect of your trip

Fast, easy, and affordable options from Panama City, FL to Sioux Falls, SD

Avg. trip duration

55 hr 10 mins

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Avg. distance

3069 km

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Cheapest trip

From 186,98 €

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2

Avg. trips a day

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On this page

Bus stations and stops in Panama City, FL

Please note: your ticket will contain the most up-to-date address information.
Best service on board
Available options you can find for a more comfortable trip:
wifi
Free WiFi
Stay connected throughout your journey
socket
Power Outlets
Keep your devices charged on the go
seat
Comfortable seats
Relax with extra legroom and reclining seats
luggage
Luggage storage
Space to safely stow your belongings
toilet
Toilets
Conveniently available on every FlixBus
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Onboard services are subject to availability

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Frequently asked questions

The latest FlixBus ride from Panama City to Sioux Falls departs at 21:40.
No, you don't need to print your ticket if you purchased it online or via the app. Simply show the driver the QR code that you received via email or that is stored in the app and you're ready to travel from Panama City to Sioux Falls. It's that easy!
There is one bus station in Sioux Falls; Sioux Falls (Jefferson Lines). You can find its location on the map on his page.
There is one bus station in Panama City; Panama City Beach Bus Station. You can find its location on the map on his page.
The earliest FlixBus ride from Panama City to Sioux Falls departs at 07:30.
FlixBus buses traveling from Panama City to Sioux Falls offer extra legroom, private outlets, and restrooms. Most buses also provide free Wi-Fi.
Traveling by bus from Panama City to Sioux Falls is one of the most environmentally-friendly options available as it reduces traffic associated emissions, and passengers can offset their carbon emissions when they travel with FlixBus by clicking the CO₂ compensation box when booking their ticket.
Yes, all FlixBus buses from Panama City to Sioux Falls are equipped for passengers with reduced mobility. We strive to make our buses as comfortable and accessible as possible for people with disabilities and limited mobility. Service animals are allowed on board all FlixBus buses traveling from Panama City to Sioux Falls. The transportation of wheelchairs, foldable wheelchairs, walking aid and other assistive mobility devices is free of charge.
The price of a children's bus ticket from Panama City to Sioux Falls depends on the age of the child and the time of booking. Children under the age of 15 receive a discount on the regular adult fare. At the time of booking, we calculate the cheapest price for you from all available rates and discounts. If the discounted price is lower than the child fare, the selected passengers pay the same price. Please, make sure you check our child travel and seat policy. Strollers and foldable pushchairs (width + length + height = max 240 cm) can be transported in the luggage compartment of the bus free of charge.
Passengers traveling from Panama City to Sioux Falls can bring one checked luggage and one piece of hand luggage for free. If you want to carry additional or special luggage, you can check all the options available on this page.
We offer several payment methods for purchasing your ticket from Panama City to Sioux Falls securely. You can choose among card payment, PayPal, Google Pay and many more. Once in the payment section, you will be able to see all the available options and pick your preferred one. If you are having difficulties with payment, check out our help page about payments. If you buy your bus ticket onboard or at a sales point you are also given the option to pay cash.
When traveling from Panama City to Sioux Falls, you can track your bus location on our Real-Time Bus Tracker. Just select the relevant bus stop and check the time of arrival. Find out where your bus is and check if there are delays on the route.
With FlixBus, you can conveniently reach 36 destinations from Sioux Falls, including Minneapolis, Rapid City, Chicago.
You can get from Panama City to Sioux Falls for as little as 186,98 €. Take advantage of our best deals on FlixBus tickets by traveling off-peak and during the week. You can buy your ticket from Panama City to Sioux Falls most easily on this website or in the app.

Looking for bus tickets from Panama City to Sioux Falls?

Look no further, we’ve got all the details you need to plan your bus trip! The journey Panama City to Sioux Falls takes as little as 50 hours 15 minutes and can cost as little as 186,98 €. The first bus leaves at 07:30 and the last bus leaves at 21:40. FlixBus runs 2 rides each day between Panama City and Sioux Falls and when travelling with FlixBus, you can expect free Wifi, power sockets and a guaranteed seat for your journey.
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