Skip to main content

Cheap bus tickets from Port St. Lucie, FL to Panama City, FL

This connection is currently unavailable.

image for unavailable city page
Where to next?
Discover our travel map with over 8000 destinations worldwide.
Explore the map
Vehicle passing through a city

Connecting you to the world

Endless possibilities. Discover over 8,000 destinations across more than 40 countries.

Comfort on the go

Kick back with free Wi-Fi, power outlets, and extra leg space. That's what modern buses are all about.

Choose, book, travel

From your screen to your seat in seconds. You do the booking, we'll take care of the rest.

Planet-smart travel

Drop the car, travel with us. Increase your mileage and reduce your carbon footprint.

Bus stations and stops in Port St. Lucie, FL

Please note: your ticket will contain the most up-to-date address information.

Looking for bus tickets from Port St. Lucie to Panama City?

Look no further, we’ve got all the details you need to plan your bus trip! The journey Port St. Lucie to Panama City takes as little as 12 hours 20 minutes and can cost as little as 57,98 €. The first bus leaves at 01:40 and the last bus leaves at 08:55. FlixBus runs 2 rides each day between Port St. Lucie and Panama City and when travelling with FlixBus, you can expect free Wifi, power sockets and a guaranteed seat for your journey.

Onboard services are subject to availability