Skip to main content

Cheap bus tickets from Rome to Brussels

from 59,99 €

Health and Safety

Keep yourself and others safe while traveling with us.
Learn more

Comfort on board

Our buses are equipped with large and comfortable seats, a toilet, Wi-Fi and power outlets.
Our onboard service

Largest bus network in Europe

Choose from over 3,000 travel destinations in 40+ countries and discover Europe with FlixBus.
Our route network

Travel environmentally-friendly

Our efficient coaches are proven to have an excellent carbon footprint per driven passenger-kilometer.
Bus travel and environment

On this page

Bus stations and stops in Rome

Please note: your ticket will contain the most up-to-date address information.

Discover all destinations

Frequently asked questions

With FlixBus, you can conveniently reach 180 destinations from Brussels, including Paris, Amsterdam, Lille.
Yes, night trip options are available from Rome to Brussels. Check out the route's schedule and choose the best option to suit your plans!
You can get from Rome to Brussels for as little as 59,99 €. Take advantage of our best deals on FlixBus tickets by traveling off-peak and during the week. You can buy your ticket from Rome to Brussels most easily on this website or in the app.
When traveling from Rome to Brussels, you can track your bus location on our Real-Time Bus Tracker. Just select the relevant bus stop and check the time of arrival. Find out where your bus is and check if there are delays on the route.
We offer several payment methods for purchasing your ticket from Rome to Brussels securely. You can choose among card payment, PayPal, Google Pay and many more. Once in the payment section, you will be able to see all the available options and pick your preferred one. If you are having difficulties with payment, check out our help page about payments. If you buy your bus ticket onboard or at a sales point you are also given the option to pay cash.
Passengers traveling from Rome to Brussels can bring one checked luggage and one piece of hand luggage for free. If you want to carry additional or special luggage, you can check all the options available on this page.
The price of a children's bus ticket from Rome to Brussels depends on the age of the child and the time of booking. Children under the age of 15 receive a discount on the regular adult fare. At the time of booking, we calculate the cheapest price for you from all available rates and discounts. If the discounted price is lower than the child fare, the selected passengers pay the same price. Please, make sure you check our child travel and seat policy. Strollers and foldable pushchairs (width + length + height = max 240 cm) can be transported in the luggage compartment of the bus free of charge.
Yes, all FlixBus buses from Rome to Brussels are equipped for passengers with reduced mobility. We strive to make our buses as comfortable and accessible as possible for people with disabilities and limited mobility. Service animals are allowed on board all FlixBus buses traveling from Rome to Brussels. The transportation of wheelchairs, foldable wheelchairs, walking aid and other assistive mobility devices is free of charge.
Traveling by bus from Rome to Brussels is one of the most environmentally-friendly options available as it reduces traffic associated emissions, and passengers can offset their carbon emissions when they travel with FlixBus by clicking the CO₂ compensation box when booking their ticket.
FlixBus buses traveling from Rome to Brussels offer extra legroom, private outlets, and restrooms. Most buses also provide free Wi-Fi.
The earliest FlixBus ride from Rome to Brussels departs at 00:10.
The latest FlixBus ride from Rome to Brussels departs at 23:50.
There are 7 bus stations in Rome; Roma Aurelia, Rome Anagnina, Rome Laurentina, Rome Piazza Indipendenza, Rome Termini, Rome Tiburtina bus station, Rome Vaticano. You can find the location of the stations on the map on this page.
No, you don't need to print your ticket if you purchased it online or via the app. Simply show the driver the QR code that you received via email or that is stored in the app and you're ready to travel from Rome to Brussels. It's that easy!
There are 4 bus stations in Brussels; Brussels Gare du Midi, Brussels Heysel (Baudouin Metro Station), Brussels South (Avenue Fonsny/Eurolines), Brussels-North train station. You can find the location of the stations on the map on this page.

Looking for bus tickets from Rome to Brussels?

Look no further, we’ve got all the details you need to plan your bus trip! The journey Rome to Brussels takes as little as 22 hours 25 minutes and can cost as little as 59,99 €. The first bus leaves at 00:10 and the last bus leaves at 23:50. FlixBus runs 21 rides each day between Rome and Brussels and when travelling with FlixBus, you can expect free Wifi, power sockets and a guaranteed seat for your journey.

Onboard services are subject to availability