Cheap bus tickets from Rome to Isernia
from 12,98 €Connecting you to the world
Endless possibilities. Discover over 8,000 destinations across more than 40 countries.
Comfort on the go
Kick back with free Wi-Fi, power outlets, and extra leg space. That's what modern buses are all about.
Choose, book, travel
From your screen to your seat in seconds. You do the booking, we'll take care of the rest.
Planet-smart travel
Drop the car, travel with us. Increase your mileage and reduce your carbon footprint.
What to expect of your trip
Fast, easy, and affordable options from Rome to Isernia
Avg. trip duration
2 hr 10 mins
Avg. distance
177 km
Cheapest trip
From 12,98 €
1
Avg. trips a day
On this page
Bus stations and stops in Rome
Rome Tiburtina bus station
Rome Anagnina
Rome Termini
Via Marsala 25
fronte Hotel Royal Santina
00185 Rome
Italy
fronte Hotel Royal Santina
00185 Rome
Italy
View this address on Google Maps
The stop is located in front of the Royal Santina Hotel (on the other side of the street)
Rome Vaticano
Rome Vaticano
Roma Aurelia
Best service on board
Available options you can find for a more comfortable trip:
Free WiFi
Stay connected throughout your journey
Power Outlets
Keep your devices charged on the go
Comfortable seats
Relax with extra legroom and reclining seats
Luggage storage
Space to safely stow your belongings
Toilets
Conveniently available on every FlixBus
First time travelling with us?
More on our service
Frequently asked questions
Is traveling by bus from Rome to Isernia environmentally-friendly?
How much is the bus ticket between Rome and Isernia?
Where can I see if my bus from Rome to Isernia is on time?
How can I pay for my bus ticket from Rome to Isernia?
How much luggage can I bring on the bus from Rome to Isernia?
How much is a children's bus ticket from Rome to Isernia?
Are the bus from Rome to Isernia equipped for passengers with reduced mobility?
What onboard services are available on buses from Rome to Isernia?
What is the earliest FlixBus ride from Rome to Isernia?
What is the latest FlixBus ride from Rome to Isernia?
How many bus stations are there in Isernia?
Do I need to print my bus ticket from Rome to Isernia?
How many bus stations are there in Rome?
Which destinations can I reach from Isernia with FlixBus?
Are weekend trips available from Rome to Isernia?
Looking for bus tickets from Rome to Isernia?
Look no further, we’ve got all the details you need to plan your bus trip! The journey Rome to Isernia takes as little as 2 hours 10 minutes and can cost as little as 12,98 €. The first bus leaves at 02:45 and the last bus leaves at 14:50. FlixBus runs 2 rides each day between Rome and Isernia and when travelling with FlixBus, you can expect free Wifi, power sockets and a guaranteed seat for your journey.Discover more popular bus connections
- Rome - Naples
- Milan - Rome
- Naples - Rome
- Rome - Florence
- Florence - Rome
- Rome - Milan
- Rome - Bari
- Bari - Rome
- Siena - Rome
- Bologna - Rome
- Rome - Siena
- Perugia - Rome
- Rome - Perugia
- Rome - Lecce
- Rome - Bologna
- Turin - Rome
- Venice - Rome
- Lecce - Rome
- Rome - Cosenza
- Cosenza - Rome
- Rome - Isernia
- Isernia - Rome
- Naples - Isernia
- Isernia - Naples
- Isernia - Pescara
- Pescara - Isernia
- Caserta - Isernia
- Florence - Isernia
- Nocera inferiore - Isernia
- Isernia - Caserta
- Isernia - Florence
- Sulmona - Isernia
- Isernia - Chieti
- Chieti - Isernia
- Isernia - Bari
- Foggia - Isernia
- Isernia - Nocera inferiore
- Isernia - Ancona
- Isernia - Rimini
- Isernia - Bologna
Onboard services are subject to availability