Skip to main content

Cheap bus tickets from Rome to Isernia

from 10,99 €

Health and Safety

Keep yourself and others safe while traveling with us.
Learn more

Comfort on board

Our buses are equipped with large and comfortable seats, a toilet, Wi-Fi and power outlets.
Our onboard service

Largest bus network in Europe

Choose from over 3,000 travel destinations in 40+ countries and discover Europe with FlixBus.
Our route network

Travel environmentally-friendly

Our efficient coaches are proven to have an excellent carbon footprint per driven passenger-kilometer.
Bus travel and environment

On this page

Bus stations and stops in Rome

Please note: your ticket will contain the most up-to-date address information.

Discover all destinations

Frequently asked questions

With FlixBus, you can conveniently reach 71 destinations from Isernia, including Rome, Naples, Foggia.
We offer several payment methods for purchasing your ticket from Rome to Isernia securely. You can choose among card payment, PayPal, Google Pay and many more. Once in the payment section, you will be able to see all the available options and pick your preferred one. If you are having difficulties with payment, check out our help page about payments. If you buy your bus ticket onboard or at a sales point you are also given the option to pay cash.
The bus route from Rome to Isernia covers 177 km. FlixBus can bring you from Rome to Isernia in 2 hours 35 minutes. The fastest bus on this connection has 1 stop(s).
You can get from Rome to Isernia for as little as 10,99 €. Take advantage of our best deals on FlixBus tickets by traveling off-peak and during the week. You can buy your ticket from Rome to Isernia most easily on this website or in the app.
When traveling from Rome to Isernia, you can track your bus location on our Real-Time Bus Tracker. Just select the relevant bus stop and check the time of arrival. Find out where your bus is and check if there are delays on the route.
Passengers traveling from Rome to Isernia can bring one checked luggage and one piece of hand luggage for free. If you want to carry additional or special luggage, you can check all the options available on this page.
The price of a children's bus ticket from Rome to Isernia depends on the age of the child and the time of booking. Children under the age of 15 receive a discount on the regular adult fare. At the time of booking, we calculate the cheapest price for you from all available rates and discounts. If the discounted price is lower than the child fare, the selected passengers pay the same price. Please, make sure you check our child travel and seat policy. Strollers and foldable pushchairs (width + length + height = max 240 cm) can be transported in the luggage compartment of the bus free of charge.
Yes, all FlixBus buses from Rome to Isernia are equipped for passengers with reduced mobility. We strive to make our buses as comfortable and accessible as possible for people with disabilities and limited mobility. Service animals are allowed on board all FlixBus buses traveling from Rome to Isernia. The transportation of wheelchairs, foldable wheelchairs, walking aid and other assistive mobility devices is free of charge.
Traveling by bus from Rome to Isernia is one of the most environmentally-friendly options available as it reduces traffic associated emissions, and passengers can offset their carbon emissions when they travel with FlixBus by clicking the CO₂ compensation box when booking their ticket.
FlixBus buses traveling from Rome to Isernia offer extra legroom, private outlets, and restrooms. Most buses also provide free Wi-Fi.
The earliest FlixBus ride from Rome to Isernia departs at 03:00.
There are 7 bus stations in Rome; Roma Aurelia, Rome Anagnina, Rome Laurentina, Rome Piazza Indipendenza, Rome Termini, Rome Tiburtina bus station, Rome Vaticano. You can find the location of the stations on the map on this page.
There are 2 bus stations in Isernia; Isernia, Isernia (Uscita Santo Spirito - Piazzale Homo Aeserniensis). You can find the location of the stations on the map on this page.
No, you don't need to print your ticket if you purchased it online or via the app. Simply show the driver the QR code that you received via email or that is stored in the app and you're ready to travel from Rome to Isernia. It's that easy!
The latest FlixBus ride from Rome to Isernia departs at 13:00.

Looking for bus tickets from Rome to Isernia?

Look no further, we’ve got all the details you need to plan your bus trip! The journey Rome to Isernia takes as little as 2 hours 35 minutes and can cost as little as 10,99 €. The first bus leaves at 03:00 and the last bus leaves at 13:00. FlixBus runs daily rides between Rome and Isernia and when travelling with FlixBus, you can expect free Wifi, power sockets and a guaranteed seat for your journey.

Onboard services are subject to availability