Looking for bus tickets from St. Louis to Des Moines?
Look no further, we’ve got all the details you need to plan your bus trip!
The journey St. Louis to Des Moines takes as little as 8 hours 15 minutes and can cost as little as 67,98 €. The first bus leaves at 01:00 and the last bus leaves at 23:30.
FlixBus runs 2 rides each day between St. Louis and Des Moines and when travelling with FlixBus, you can expect free Wifi, power sockets and a guaranteed seat for your journey.