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Cheap bus tickets from Tupelo, MS to Des Moines, IA

from 85,98 €

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What to expect of your trip

Fast, easy, and affordable options from Tupelo, MS to Des Moines, IA

Min. trip duration

17 hr 40 mins

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Min. distance

1336 km

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Cheapest trip

From 85,98 €

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3

Min. trips a day

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On this page

Bus stations and stops in Tupelo, MS

Please note: your ticket will contain the most up-to-date address information.
Best service on board
Available options you can find for a more comfortable trip:
wifi
Free WiFi
Stay connected throughout your journey
socket
Power Outlets
Keep your devices charged on the go
seat
Comfortable seats
Relax with extra legroom and reclining seats
luggage
Luggage storage
Space to safely stow your belongings
toilet
Toilets
Conveniently available on every FlixBus
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Onboard services are subject to availability

Where to next?
Discover our travel map with over 8000 destinations worldwide.
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Vehicle passing through a city

Digital ticket & Live tracking

Discover the FlixBus app

Book trips
Your tickets
Track your trip
Always in-the-know
Get it on Google Play Download on the App Store
FlixBus app on phone

Scan to download the App

Trusted by 500+ million passengers

Frequently asked questions

The bus route from Tupelo to Des Moines covers 1336 km. FlixBus can bring you from Tupelo to Des Moines in 17 hours 40 minutes.
Bus ticket prices from Tupelo to Des Moines can vary depending on your travel date, time, and how early you book. You can find bus tickets starting from as little as 91,98 €.
When traveling from Tupelo to Des Moines, you can track your bus location on our Real-Time Bus Tracker. Just select the relevant bus stop and check the time of arrival. Find out where your bus is and check if there are delays on the route.
We offer several secure payment methods for purchasing your ticket from Tupelo to Des Moines. You can pay using debit or credit card, PayPal, Google Pay, and other options. All available payment methods will be displayed during checkout so you can choose the one that suits you best. If you experience payment issues, check that your payment details are correct, your card is enabled for online or international transactions, and that you have sufficient funds. If you buy your bus ticket onboard or at a sales point, you may also have the option to pay in cash.
Passengers traveling from Tupelo to Des Moines with FlixBus can bring one piece of checked luggage and one piece of hand luggage free of charge. Your hand luggage should fit in the overhead compartment or under your seat, while larger bags are stored in the bus’s luggage compartment. If you want to bring additional or special luggage, you can find all available options on our luggage allowance.
Traveling by bus from Tupelo to Des Moines is one of the most environmentally-friendly options available as it reduces traffic associated emissions, and passengers can offset their carbon emissions when they travel with FlixBus by clicking the CO₂ compensation box when booking their ticket.
FlixBus buses traveling from Tupelo to Des Moines offer extra legroom, private outlets, and restrooms. Most buses also provide free Wi-Fi.
The first FlixBus from Tupelo to Des Moines departs at 05:35, while the last departure is at 21:45. Departure times may vary depending on the day and route, so it’s always advisable to check the schedule before you book your bus ticket.
There is one bus station in Des Moines. You can find its location on the map on his page.
There is one bus stop in Tupelo. You can find its location on the map on his page.
No, you don't need to print your ticket if you purchased it online or via the app. Simply show the driver the QR code that you received via email or that is stored in the app and you're ready to travel from Tupelo to Des Moines. It's that easy!
With FlixBus, you can conveniently reach 62 destinations from Des Moines, including Chicago, Minneapolis, Iowa City.
Yes, weekend trip options are available from Tupelo to Des Moines. Check out the route's schedule and chose the best option to suit your plans!

Looking for bus tickets from Tupelo to Des Moines?

Look no further, we’ve got all the details you need to plan your bus trip! The journey Tupelo to Des Moines takes as little as 17 hours 40 minutes and can cost as little as 91,98 €. The first bus leaves at 05:35 and the last bus leaves at 21:45. FlixBus runs 3 rides each day between Tupelo and Des Moines and when travelling with FlixBus, you can expect free Wifi, power sockets and a guaranteed seat for your journey.