Cheap bus tickets from Lyon to Isernia
from 56,46 €Connecting you to the world
Endless possibilities. Discover over 8,000 destinations across more than 40 countries.
Comfort on the go
Kick back with free Wi-Fi, power outlets, and extra leg space. That's what modern buses are all about.
Choose, book, travel
From your screen to your seat in seconds. You do the booking, we'll take care of the rest.
Planet-smart travel
Drop the car, travel with us. Increase your mileage and reduce your carbon footprint.
What to expect of your trip
Fast, easy, and affordable options from Lyon to Isernia
Bus stations and stops in Lyon
Lyon Perrache (Galerie D)
Gare Routière de Lyon Perrache, Cours de Verdun
Galerie D
69002 Lyon
France
Galerie D
69002 Lyon
France
View this address on Google Maps
1st floor - Gallery D. How to access to the platforms: https://bit.ly/4aSEZik from the metro or https://bit.ly/3XgJBf4 from the SNCF station - Attention: all departures between 00:30 and 04:45 will be operated at the Kitchener-Marchand bridge (1 Cours de Verdun Gensoul): https://bit.ly/4euuULz
Lyon (Gerland Bus Station)
52 Avenue Tony Garnier
Gare Routière Internationale de Lyon Gerland
69007 Lyon
France
Gare Routière Internationale de Lyon Gerland
69007 Lyon
France
View this address on Google Maps
From January 12 of 2026, the FlixBus stop in Lyon is relocated at Gerland station.
Givors (South Lyon)
Best service on board
Available options you can find for a more comfortable trip:
Free WiFi
Stay connected throughout your journey
Power Outlets
Keep your devices charged on the go
Comfortable seats
Relax with extra legroom and reclining seats
Luggage storage
Space to safely stow your belongings
Toilets
Conveniently available on every FlixBus
First time travelling with us?
More on our service
Frequently asked questions
How long does it take from Lyon to Isernia by bus?
Do I need to print my bus ticket from Lyon to Isernia?
How many bus stations are there in Lyon?
What is the latest FlixBus ride from Lyon to Isernia?
What is the earliest FlixBus ride from Lyon to Isernia?
How many bus stations are there in Isernia?
Is traveling by bus from Lyon to Isernia environmentally-friendly?
What onboard services are available on buses from Lyon to Isernia?
Where can I see if my bus from Lyon to Isernia is on time?
How much does it cost to take a bike on the bus from Lyon to Isernia?
How much is the bus ticket between Lyon and Isernia?
How much luggage can I bring on the bus from Lyon to Isernia?
How much is a children's bus ticket from Lyon to Isernia?
Are the bus from Lyon to Isernia equipped for passengers with reduced mobility?
How can I pay for my bus ticket from Lyon to Isernia?
Discover more popular bus connections
- Lyon - Grenoble
- Paris - Lyon
- Grenoble - Lyon
- Lyon - Paris
- Clermont-Ferrand - Lyon
- Lyon - Clermont-Ferrand
- Annecy - Lyon
- Turin - Lyon
- Lyon - Annecy
- Geneva - Lyon
- Lyon - Marseille
- Lyon - Geneva
- Lyon - Turin
- Marseille - Lyon
- Lyon - Milan
- Montpellier - Lyon
- Milan - Lyon
- Lyon - Montpellier
- Barcelona - Lyon
- Lyon - Strasbourg
- Naples - Isernia
- Isernia - Rome
- Rome - Isernia
- Isernia - Naples
- Florence - Isernia
- Pescara - Isernia
- Milan - Isernia
- Isernia - Florence
- Isernia - Bari
- Isernia - Foggia
- Ancona - Isernia
- Isernia - Pescara
- Foggia - Isernia
- Nocera inferiore - Isernia
- Isernia - Forlì
- Genoa - Isernia
- Salerno - Isernia
- Isernia - Caserta
- Caserta - Isernia
- Isernia - Salerno
Onboard services are subject to availability