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Cheap bus tickets from Pisa to Isernia

from 26,97 €

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What to expect of your trip

Fast, easy, and affordable options from Pisa to Isernia

Avg. trip duration

12 hr 28 mins

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Avg. distance

638 km

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Cheapest trip

From 26,97 €

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3

Avg. trips a day

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Bus stations and stops in Pisa

Please note: your ticket will contain the most up-to-date address information.
Best service on board
Available options you can find for a more comfortable trip:
wifi
Free WiFi
Stay connected throughout your journey
socket
Power Outlets
Keep your devices charged on the go
seat
Comfortable seats
Relax with extra legroom and reclining seats
luggage
Luggage storage
Space to safely stow your belongings
toilet
Toilets
Conveniently available on every FlixBus
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Onboard services are subject to availability

Where to next?
Discover our travel map with over 8000 destinations worldwide.
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Vehicle passing through a city

Digital ticket & Live tracking

Discover the FlixBus app

Book trips
Your tickets
Track your trip
Always in-the-know
Get it on Google Play Download on the App Store
FlixBus app on phone

Scan to download the App

Trusted by 500+ million passengers

Frequently asked questions

No, you don't need to print your ticket if you purchased it online or via the app. Simply show the driver the QR code that you received via email or that is stored in the app and you're ready to travel from Pisa to Isernia. It's that easy!
There are 2 bus stations in Isernia; Isernia, Isernia (Uscita Santo Spirito - Piazzale Homo Aeserniensis). You can find the location of the stations on the map on this page.
There are 4 bus stations in Pisa; Pisa (Pietrasantina car park), Pisa (Pisamover via San Giusto/Aurelia), Pisa (Train station/City Center), Pisa Ospedale Cisanello. You can find the location of the stations on the map on this page.
The latest FlixBus ride from Pisa to Isernia departs at 22:00.
Yes, night trip options are available from Pisa to Isernia. Check out the route's schedule and choose the best option to suit your plans!
With FlixBus, you can conveniently reach 73 destinations from Isernia, including Rome, Naples, Pescara.
The earliest FlixBus ride from Pisa to Isernia departs at 04:45.
You can get from Pisa to Isernia for as little as 26,97 €. Take advantage of our best deals on FlixBus tickets by traveling off-peak and during the week. You can buy your ticket from Pisa to Isernia most easily on this website or in the app.
When traveling from Pisa to Isernia, you can track your bus location on our Real-Time Bus Tracker. Just select the relevant bus stop and check the time of arrival. Find out where your bus is and check if there are delays on the route.
We offer several payment methods for purchasing your ticket from Pisa to Isernia securely. You can choose among card payment, PayPal, Google Pay and many more. Once in the payment section, you will be able to see all the available options and pick your preferred one. If you are having difficulties with payment, check out our help page about payments. If you buy your bus ticket onboard or at a sales point you are also given the option to pay cash.
Passengers traveling from Pisa to Isernia can bring one checked luggage and one piece of hand luggage for free. If you want to carry additional or special luggage, you can check all the options available on this page.
FlixBus buses traveling from Pisa to Isernia offer extra legroom, private outlets, and restrooms. Most buses also provide free Wi-Fi.
Traveling by bus from Pisa to Isernia is one of the most environmentally-friendly options available as it reduces traffic associated emissions, and passengers can offset their carbon emissions when they travel with FlixBus by clicking the CO₂ compensation box when booking their ticket.
The price of a children's bus ticket from Pisa to Isernia depends on the age of the child and the time of booking. Children under the age of 15 receive a discount on the regular adult fare. At the time of booking, we calculate the cheapest price for you from all available rates and discounts. If the discounted price is lower than the child fare, the selected passengers pay the same price. Please, make sure you check our child travel and seat policy. Strollers and foldable pushchairs (width + length + height = max 240 cm) can be transported in the luggage compartment of the bus free of charge.
Yes, all FlixBus buses from Pisa to Isernia are equipped for passengers with reduced mobility. We strive to make our buses as comfortable and accessible as possible for people with disabilities and limited mobility. Service animals are allowed on board all FlixBus buses traveling from Pisa to Isernia. The transportation of wheelchairs, foldable wheelchairs, walking aid and other assistive mobility devices is free of charge.

Looking for bus tickets from Pisa to Isernia?

Look no further, we’ve got all the details you need to plan your bus trip! The journey Pisa to Isernia takes as little as 11 hours 10 minutes and can cost as little as 26,97 €. The first bus leaves at 04:45 and the last bus leaves at 22:00. FlixBus runs 3 rides each day between Pisa and Isernia and when travelling with FlixBus, you can expect free Wifi, power sockets and a guaranteed seat for your journey.