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Cheap bus tickets from Santa Cruz to Santiago

from 5,98 €

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What to expect of your trip

Fast, easy, and affordable options from Santa Cruz to Santiago

Avg. trip duration

2hr24mins

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Avg. distance

164 km

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Cheapest trip

From 5,98 €

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13

Avg. trips a day

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On this page

Bus stations and stops in Santa Cruz

Please note: your ticket will contain the most up-to-date address information.
Best service on board
Available options you can find for a more comfortable trip:
wifi
Free WiFi
Stay connected throughout your journey
socket
Power Outlets
Keep your devices charged on the go
seat
Comfortable seats
Relax with extra legroom and reclining seats
luggage
Luggage storage
Space to safely stow your belongings
toilet
Toilets
Conveniently available on every FlixBus
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Frequently asked questions

Traveling by bus from Santa Cruz to Santiago is one of the most environmentally-friendly options available as it reduces traffic associated emissions, and passengers can offset their carbon emissions when they travel with FlixBus by clicking the CO₂ compensation box when booking their ticket.
You can get from Santa Cruz to Santiago for as little as 5,98 €. Take advantage of our best deals on FlixBus tickets by traveling off-peak and during the week. You can buy your ticket from Santa Cruz to Santiago most easily on this website or in the app.
When traveling from Santa Cruz to Santiago, you can track your bus location on our Real-Time Bus Tracker. Just select the relevant bus stop and check the time of arrival. Find out where your bus is and check if there are delays on the route.
We offer several payment methods for purchasing your ticket from Santa Cruz to Santiago securely. You can choose among card payment, PayPal, Google Pay and many more. Once in the payment section, you will be able to see all the available options and pick your preferred one. If you are having difficulties with payment, check out our help page about payments. If you buy your bus ticket onboard or at a sales point you are also given the option to pay cash.
Passengers traveling from Santa Cruz to Santiago can bring one checked luggage and one piece of hand luggage for free. If you want to carry additional or special luggage, you can check all the options available on this page.
The price of a children's bus ticket from Santa Cruz to Santiago depends on the age of the child and the time of booking. Children under the age of 15 receive a discount on the regular adult fare. At the time of booking, we calculate the cheapest price for you from all available rates and discounts. If the discounted price is lower than the child fare, the selected passengers pay the same price. Please, make sure you check our child travel and seat policy. Strollers and foldable pushchairs (width + length + height = max 240 cm) can be transported in the luggage compartment of the bus free of charge.
Yes, all FlixBus buses from Santa Cruz to Santiago are equipped for passengers with reduced mobility. We strive to make our buses as comfortable and accessible as possible for people with disabilities and limited mobility. Service animals are allowed on board all FlixBus buses traveling from Santa Cruz to Santiago. The transportation of wheelchairs, foldable wheelchairs, walking aid and other assistive mobility devices is free of charge.
FlixBus buses traveling from Santa Cruz to Santiago offer extra legroom, private outlets, and restrooms. Most buses also provide free Wi-Fi.
The earliest FlixBus ride from Santa Cruz to Santiago departs at 05:00.
The latest FlixBus ride from Santa Cruz to Santiago departs at 18:00.
There are 6 bus stations in Santiago; Cruce Colón, Santiago (Los Libertadores), Santiago (Pajaritos), Santiago (Terminal Del Sol), Santiago (Terminal San Borja), Santiago (Terminal Sur). You can find the location of the stations on the map on this page.
No, you don't need to print your ticket if you purchased it online or via the app. Simply show the driver the QR code that you received via email or that is stored in the app and you're ready to travel from Santa Cruz to Santiago. It's that easy!
There is one bus station in Santa Cruz; Santa Cruz (Terminal de Buses). You can find its location on the map on his page.
With FlixBus, you can conveniently reach 44 destinations from Santiago, including Viña del Mar, Valparaíso, Curico.
Yes, weekend trip options are available from Santa Cruz to Santiago. Check out the route's schedule and chose the best option to suit your plans!

Looking for bus tickets from Santa Cruz to Santiago?

Look no further, we’ve got all the details you need to plan your bus trip! The journey Santa Cruz to Santiago takes as little as 2 hours 24 minutes and can cost as little as 5,98 €. The first bus leaves at 05:00 and the last bus leaves at 18:00. FlixBus runs 14 rides each day between Santa Cruz and Santiago and when travelling with FlixBus, you can expect free Wifi, power sockets and a guaranteed seat for your journey.
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Onboard services are subject to availability