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Cheap bus tickets from Santiago to La Serena

from 9,99 €

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Bus stations and stops in Santiago

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Frequently asked questions

With FlixBus, you can conveniently reach 4 destinations from La Serena, including Santiago, Viña del Mar, Valparaíso.
Yes, weekend trip options are available from Santiago to La Serena. Check out the route's schedule and chose the best option to suit your plans!
Yes, night trip options are available from Santiago to La Serena. Check out the route's schedule and choose the best option to suit your plans!
No, you don't need to print your ticket if you purchased it online or via the app. Simply show the driver the QR code that you received via email or that is stored in the app and you're ready to travel from Santiago to La Serena. It's that easy!
You can get from Santiago to La Serena for as little as 9,99 €. Take advantage of our best deals on FlixBus tickets by traveling off-peak and during the week. You can buy your ticket from Santiago to La Serena most easily on this website or in the app.
When traveling from Santiago to La Serena, you can track your bus location on our Real-Time Bus Tracker. Just select the relevant bus stop and check the time of arrival. Find out where your bus is and check if there are delays on the route.
We offer several payment methods for purchasing your ticket from Santiago to La Serena securely. You can choose among card payment, PayPal, Google Pay and many more. Once in the payment section, you will be able to see all the available options and pick your preferred one. If you are having difficulties with payment, check out our help page about payments. If you buy your bus ticket onboard or at a sales point you are also given the option to pay cash.
Passengers traveling from Santiago to La Serena can bring one checked luggage and one piece of hand luggage for free. If you want to carry additional or special luggage, you can check all the options available on this page.
The price of a children's bus ticket from Santiago to La Serena depends on the age of the child and the time of booking. Children under the age of 15 receive a discount on the regular adult fare. At the time of booking, we calculate the cheapest price for you from all available rates and discounts. If the discounted price is lower than the child fare, the selected passengers pay the same price. Please, make sure you check our child travel and seat policy. Strollers and foldable pushchairs (width + length + height = max 240 cm) can be transported in the luggage compartment of the bus free of charge.
Yes, all FlixBus buses from Santiago to La Serena are equipped for passengers with reduced mobility. We strive to make our buses as comfortable and accessible as possible for people with disabilities and limited mobility. Service animals are allowed on board all FlixBus buses traveling from Santiago to La Serena. The transportation of wheelchairs, foldable wheelchairs, walking aid and other assistive mobility devices is free of charge.
Traveling by bus from Santiago to La Serena is one of the most environmentally-friendly options available as it reduces traffic associated emissions, and passengers can offset their carbon emissions when they travel with FlixBus by clicking the CO₂ compensation box when booking their ticket.
FlixBus buses traveling from Santiago to La Serena offer extra legroom, private outlets, and restrooms. Most buses also provide free Wi-Fi.
The earliest FlixBus ride from Santiago to La Serena departs at 06:15.
The latest FlixBus ride from Santiago to La Serena departs at 23:59.
There are 5 bus stations in Santiago; Santiago (Cruce Colon), Santiago (Los Libertadores), Santiago (Pajaritos), Santiago (Terminal Del Sol), Santiago (Terminal San Borja). You can find the location of the stations on the map on this page.
There is one bus station in La Serena; La Serena (Bus terminal La Serena). You can find its location on the map on his page.
The bus route from Santiago to La Serena covers 472 km. FlixBus can bring you from Santiago to La Serena in 5 hours 35 minutes. The fastest bus on this connection has 2 stop(s).

Looking for bus tickets from Santiago to La Serena?

Look no further, we’ve got all the details you need to plan your bus trip! The journey Santiago to La Serena takes as little as 5 hours 35 minutes and can cost as little as 9,99 €. The first bus leaves at 06:15 and the last bus leaves at 23:59. FlixBus runs 10 rides each day between Santiago and La Serena and when travelling with FlixBus, you can expect free Wifi, power sockets and a guaranteed seat for your journey.

Onboard services are subject to availability