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Cheap bus tickets from Antofagasta to Santa Cruz

from 33,98 €

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What to expect of your trip

Fast, easy, and affordable options from Antofagasta to Santa Cruz

Avg. trip duration

24 hr 32 mins

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Avg. distance

1558 km

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Cheapest trip

From 33,98 €

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1

Avg. trips a day

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Bus stations and stops in Antofagasta

Please note: your ticket will contain the most up-to-date address information.
Best service on board
Available options you can find for a more comfortable trip:
wifi
Free WiFi
Stay connected throughout your journey
socket
Power Outlets
Keep your devices charged on the go
seat
Comfortable seats
Relax with extra legroom and reclining seats
luggage
Luggage storage
Space to safely stow your belongings
toilet
Toilets
Conveniently available on every FlixBus
First time travelling with us?
More on our service
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Onboard services are subject to availability

Where to next?
Discover our travel map with over 8000 destinations worldwide.
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Vehicle passing through a city

Digital ticket & Live tracking

Discover the FlixBus app

Book trips
Your tickets
Track your trip
Always in-the-know
Get it on Google Play Download on the App Store
FlixBus app on phone

Scan to download the App

Trusted by 500+ million passengers

Frequently asked questions

Traveling by bus from Antofagasta to Santa Cruz is one of the most environmentally-friendly options available as it reduces traffic associated emissions, and passengers can offset their carbon emissions when they travel with FlixBus by clicking the CO₂ compensation box when booking their ticket.
No, you don't need to print your ticket if you purchased it online or via the app. Simply show the driver the QR code that you received via email or that is stored in the app and you're ready to travel from Antofagasta to Santa Cruz. It's that easy!
There is one bus station in Santa Cruz; Santa Cruz (Terminal de Buses). You can find its location on the map on his page.
There is one bus station in Antofagasta; Antofagasta (Terminal de Buses Cardenal Carlos Oviedo Cavada). You can find its location on the map on his page.
The latest FlixBus ride from Antofagasta to Santa Cruz departs at 21:50.
The earliest FlixBus ride from Antofagasta to Santa Cruz departs at 18:20.
FlixBus buses traveling from Antofagasta to Santa Cruz offer extra legroom, private outlets, and restrooms. Most buses also provide free Wi-Fi.
Yes, all FlixBus buses from Antofagasta to Santa Cruz are equipped for passengers with reduced mobility. We strive to make our buses as comfortable and accessible as possible for people with disabilities and limited mobility. Service animals are allowed on board all FlixBus buses traveling from Antofagasta to Santa Cruz. The transportation of wheelchairs, foldable wheelchairs, walking aid and other assistive mobility devices is free of charge.
The price of a children's bus ticket from Antofagasta to Santa Cruz depends on the age of the child and the time of booking. Children under the age of 15 receive a discount on the regular adult fare. At the time of booking, we calculate the cheapest price for you from all available rates and discounts. If the discounted price is lower than the child fare, the selected passengers pay the same price. Please, make sure you check our child travel and seat policy. Strollers and foldable pushchairs (width + length + height = max 240 cm) can be transported in the luggage compartment of the bus free of charge.
We offer several payment methods for purchasing your ticket from Antofagasta to Santa Cruz securely. You can choose among card payment, PayPal, Google Pay and many more. Once in the payment section, you will be able to see all the available options and pick your preferred one. If you are having difficulties with payment, check out our help page about payments. If you buy your bus ticket onboard or at a sales point you are also given the option to pay cash.
When traveling from Antofagasta to Santa Cruz, you can track your bus location on our Real-Time Bus Tracker. Just select the relevant bus stop and check the time of arrival. Find out where your bus is and check if there are delays on the route.
You can get from Antofagasta to Santa Cruz for as little as 33,98 €. Take advantage of our best deals on FlixBus tickets by traveling off-peak and during the week. You can buy your ticket from Antofagasta to Santa Cruz most easily on this website or in the app.
Passengers traveling from Antofagasta to Santa Cruz can bring one checked luggage and one piece of hand luggage for free. If you want to carry additional or special luggage, you can check all the options available on this page.
Yes, weekend trip options are available from Antofagasta to Santa Cruz. Check out the route's schedule and chose the best option to suit your plans!
With FlixBus, you can conveniently reach 6 destinations from Santa Cruz, including Santiago, San Fernando, Rancagua.

Looking for bus tickets from Antofagasta to Santa Cruz?

Look no further, we’ve got all the details you need to plan your bus trip! The journey Antofagasta to Santa Cruz takes as little as 23 hours 40 minutes and can cost as little as 33,98 €. The first bus leaves at 18:20 and the last bus leaves at 21:50. FlixBus runs daily rides between Antofagasta and Santa Cruz and when travelling with FlixBus, you can expect free Wifi, power sockets and a guaranteed seat for your journey.